Common blood cancer may be initiated by single mutation in bone cells

AML is a blood cancer, but for many patients the cancer may originate from an unusual source: a mutation in their bone cells. In a study published, researchers explain that a mutation in the bone cells called osteoblasts, which build new bone, causes AML in mice. The mutation was found in nearly 40 percent of patients with AML or myelodysplastic syndrome, a precursor condition, who were examined as part of the study.