Epigenetic regulation required to ensure correct number of chromosomes

Abnormal number of chromosomes is often associated with cancer development. Researchers have shown that a subtle epigenetic change plays an important role in the correct segregation of chromosomes. Normally when a cell divides, the chromosomes are segregated equally to two daughter cells. However, tumor cells frequently have either too few or too many chromosomes, leading to the incorrect expression of a number of genes. When a cell is about to divide, the cell division machinery takes hold of c...