Lymphoid cells discovered in human spleen, essential for production of antibodies

Researchers have discovered the presence of a novel subtype of innate lymphoid cells in human spleen essential for the production of antibodies. This discovery clears the path to the identification of novel strategies to develop more efficient vaccines against encapsulated bacteria, considered highly virulent. This research involved in vitro studies with isolated cells from human spleen samples and in vivo studies performed with different mice models.