Protein key to cell motility has implications for stopping cancer metastasis

A key cell-movement protein called IRSp53, as described by researchers, is regulated in a resting and active state, and in a new study, they address what this means for cancer-cell metastasis. "We characterized how IRSp53 connects to the cell-motility machinery," says an author. "It does this by starting the formation of cell filopodia -- extensions that form when a cell needs to move."