Potential Combination Therapy for Aggressive Thyroid Cancer

A novel mouse model of anaplastic thyroid cancer has been developed by scientists who have also identified a combination of targeted therapies that shrinks these tumors. Most patients diagnosed with thyroid cancer do very well, but in a small fraction of patients it evolves into aggressive forms of thyroid cancer. Among these, the extremely aggressive human ATC is associated with one of the worst prognoses of any kind of human cancer.