Source of most cases of invasive bladder cancer identified

A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers. The study, conducted in mice, is the first to pinpoint the normal cell type that can give rise to invasive bladder cancers. It's also the first to show that most bladder cancers and their associated precancerous lesions arise from just one cell, and explains why many human bladder cancers recur after therapy.