Approach used to conduct meta-analyses may affect outcomes

Depending on the analysis strategy used, estimating treatment outcomes in meta-­analyses may differ and may result in major alterations in the conclusions derived from the analysis, according to a study. Meta-analyses of randomized clinical trials (RCTs) are generally considered to provide among the best evidence of efficacy of medical interventions. They should be conducted as part of a systematic review, a scientifically rigorous approach that identifies, selects, and appraises all relevant s...