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An analysis of all of the previous trials to date has been conducted to better define both the benefits and risks of the competing anticoagulants. Researchers found that, compared with heparin-based regimens, bivalirudin-based regimens increased the risk of heart attack and stent thrombosis. Bivalirudin-based regimens decreased the risk of bleeding, but by how much depended on whether other blood thinners were used more with heparin than with bivalirudin.
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