HSP90 is a potential target for ameliorating skeletal muscle abnormalities in PD

(Neural Regeneration Research) Heat shock protein (HSP90) has been suggested to be involved in neuronal protein misfolding and accumulation in Parkinson's disease (PD) brains leading to dopaminergic neuronal death and the eventual dopamine depletion. Therefore, HSP90 has been suggested as a therapeutic target in PD.