Colorful nano-guides to the liver

Jena scientists have been successful in producing highly specific nanoparticles. Depending on the bound dye the particles are guided to the liver or to the kidney and deliver their payload of active ingredients directly to the targeted tissue. Moreover, the dyes enable the tracking of the transport processes by intravital microscopy or, in a non-invasive way, by multi spectral optoacoustic tomography. The reduction of cholesterol production induced by siRNA served as the proof-of-principle for t...