Decreases in short-term memory, IQ, altered brain metabolic ratios in urban APOE4 children

(IOS Press) A new study by researchers at the Universities of Montana, Carleton, and North Carolina, and the Centro de Ciencias de la Atmósfera, Universidad Nacional Autónoma de México, heightens concerns over the detrimental impact of the apolipoprotein E (APOE) ε4 allele -- the most prevalent genetic risk for Alzheimer's disease -- upon cognition, olfaction, and metabolic brain indices in healthy urban children and teens. These findings are published in the Journal of Alzheimer's Disease.