Akt Pathway 'ramp ups' effects of transplanted umbilical cord cells used in stroke therapy

(Cell Transplantation Center of Excellence for Aging and Brain Repair) Researchers found that transplanted human umbilical cord blood cells (HUCBCs) are beneficial in preventing neuron loss when the Akt signaling pathway is activated by HUCBC secretions, and the subsequent Akt activation impacts a specific gene involved in reducing inflammation. A reduction in inflammation helps neural cell survival following stroke. The Akt pathway has been shown to be important because it activates the peroxir...