Proteomics identifies DNA repair toolbox

(Max Planck Institute of Biochemistry) Various repair mechanisms help our cells to revert continuous damage to their DNA. If they fail, mutations accumulate that can lead to devastating diseases. DNA repair defects underlie predisposition to certain cancers and promote the transformation process in other spontaneous cancers. Using highly sensitive proteomic technologies, scientists of the Max Planck Institute of Biochemistry now report in the journal Science the first global analysis of the prot...