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Milestone single-biomolecule imaging technique may advance drug design Knowing the detailed shape of biomolecules such as proteins is essential for biological studies and drug discovery. Modern structural biology relies on techniques such as nuclear magnetic resonance (NMR), X-ray crystallography and cryo-electron microscopy to discover the tiny structural details of biomolecules. All these methods, however, require averaging over a large number of molecules and thus structural details of an individual biomolecule are often lost.
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