Can stem cell technology be harnessed to generate biological pacemakers?

Although today's pacemakers are lifesaving electronic devices, they are limited by their artificial nature. For example, the devices require regular maintenance, must be replaced periodically, and can only approximate the natural regulation of a heartbeat. A new article highlights the promise and limitations of new methods based on stem cell and reprogramming technologies to generate biological pacemakers that might one day replace electronic pacemakers.