The expression of about three-quarters of active genes in a cell is controlled by a process in which the DNA-transcribing enzyme hesitates before going to work. Experiments have identified the complex of proteins that helps restart this enzyme when it stalls, and so helped to explain how some promising cancer drugs work.
New aspect of gene regulation, possible target for cancer drugs discovered
Science Daily - 10 Dec 2015 21:47
The expression of about three-quarters of active genes in a cell is controlled by a process in which the DNA-transcribing enzyme hesitates before going to work. Experiments have identified the complex of proteins that helps restart this enzyme when it stalls, and so helped to explain how some promising cancer drugs work.
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