UMMS scientists reveal new phase of HIV infection

(University of Massachusetts Medical School) Researchers at the UMass Medical School have identified a new life cycle stage in HIV infection thanks to a novel technique they developed to take images of intact infected cells. They've shown that this phase of infection, dubbed intra-nuclear migration, relies on the human protein CPSF6 to guide the virus through the host cell's nucleus and position it at active genes where it prefers to make its home.