In vitro tests of Vype vapor reveal no cell stress, DNA damage or cell transformation

(R&D at British American Tobacco) A series of cell-based tests developed to compare the biological impact of cigarette smoke with e-cigarette vapor revealed no activity in cells exposed to vapor from Vype ePen, a commercially available e-cigarette. In contrast, when the cell culture systems were exposed to cigarette smoke, they exhibited a series of responses including stress responses, DNA damage and malignant transformation, depending on the assay used.