Avoiding mixtures of different mitochondria leads to effective mitochondrial replacement

Scientists have discovered an important biological phenomenon in human cells that will help scientists design safer treatments to prevent mitochondrial diseases. The team first pioneered a technique, mitochondrial replacement therapy (MRT), in 2012 to prevent inheritance of these devastating and debilitating diseases. Now they are working to hone this technique and understand the biological processes that would impact patients as this process is brought into clinical trials.