A combined approach to treating metastatic melanoma

(Rockefeller University Press) Oncologists at the Fred Hutchinson Cancer Research Center have successfully treated a patient with metastatic melanoma by combining two different types of immunotherapy. Cassian Yee and colleagues describe their approach in a paper, 'Combined IL-21-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient,' that will be published online May 30 in The Journal of Experimental Medicine.