In mice, daughters of overweight dads have altered breast tissue, higher cancer risk

(Georgetown University Medical Center) Obese male mice and normal weight female mice produce female pups that are overweight at birth through childhood, and have delayed development of their breast tissue as well as increased rates of breast cancer. The findings, published online June 24 in Scientific Reports by Georgetown Lombardi Comprehensive Cancer Center researchers, come from one of the first animal studies to examine the impact of paternal obesity on future generations' cancer risk.