Computational modelling can predict onset, progression of knee osteoarthritis in overweight people

Computational modelling makes it possible to predict the onset and progression of knee osteoarthritis in overweight people, shows a new study. A computational model based on the degradation of the collagen fibril network in the articular cartilage was able to predict the onset and progression of osteoarthritis in overweight people during a four-year follow-up. In normal-weight people, osteoarthritis did not develop within this time span.