Scientists at the Movies: Third Rock, D.E. Shaw Bet $57M on Protein Motion for Drug Discovery

Snapshot images of molecular targets are crucial tools of the drug discovery business. The vivid 3-D architecture of a disease-related protein is a good starting point to develop drugs that bind properly with the target. Drug discovery, to use some common metaphors, is about making keys to fit into specific biological locks, or finding the right handhold or toehold.