Exosomes are the missing link to insulin resistance in diabetes

(University of California - San Diego) Chronic tissue inflammation resulting from obesity is an underlying cause of insulin resistance and type 2 diabetes. But the mechanism by which this occurs has remained cloaked, until now. In a paper, published in the journal Cell, University of California San Diego School of Medicine researchers identified exosomes -- extremely small vesicles or sacs secreted from most cell types -- as the missing link.