Link found between estrogens and changes in heart physiology

(University of Alabama at Birmingham) Working at the UAB Zebrafish Research Facility, Daniel Gorelick, assistant professor of pharmacology and toxicology, has created zebrafish mutants in four different receptors -- found inside or on the surface of cells -- that respond to estrogens, and he has used the mutants to help unravel a novel mechanism of estrogen action on heart physiology. Broader use of the mutants may have significant implications for studies of estrogenic environmental endocrine d...