Recently developed computational strategies could help realize the promise of peptide-based drugs. Researchers were able to sample the diverse landscape of shapes that peptides can form as a guide for designing the next generation of stable, potent, selective drugs. They compiled a library of peptide scaffolds upon which drug candidates might be designed. Their methods also can be used to design additional custom peptides with arbitrary shapes on demand.
Computational strategies overcome obstacles in peptide therapeutics development
Science Daily - 14 Dec 2017 23:40
Recently developed computational strategies could help realize the promise of peptide-based drugs. Researchers were able to sample the diverse landscape of shapes that peptides can form as a guide for designing the next generation of stable, potent, selective drugs. They compiled a library of peptide scaffolds upon which drug candidates might be designed. Their methods also can be used to design additional custom peptides with arbitrary shapes on demand.
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