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How some liver cells switch identities to build missing plumbing By studying a rare liver disease called Alagille syndrome, scientists discovered the mechanism behind a form of tissue regeneration that may someday reduce the need for organ transplants. Researchers report that when disease or injury causes a shortage in one type of liver cell, the organ can instruct another type of liver cell to change identities to provide replacement supplies. The findings one day may lead to a viable treatment for human disease.
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