Journal of Neuroscience study explains what makes aggressive mice so violent

(The Mount Sinai Hospital / Mount Sinai School of Medicine) Higher levels of FosB in NAc neurons were associated with more intense behaviors by aggressive mice defending their home cage from an intruder. Overexpressing FosB in aggressive mice also increased their dominance over an opponent when they faced each other in a narrow tube. While increased FosB in dopamine D1 receptor expressing medium spiny neurons (D1-MSNs) was associated with increased aggression intensity, mice with increased FosB ...