Speeding up single-cell genomics research

Time-saving method makes it possible to profile gene regulation in tens of thousands of individual human cells in a single day. Approach combines microfluidics and novel software to scale up single-cell ATAC-seq, which identifies parts of the tightly packaged genome that are more open and accessible to regulatory proteins. Profiling individual cells can clarify how genes function - in which specific cell types, at what time - and whether they play a role in disease.