Diet trials often amend their outcome measures as they go

(Boston Children's Hospital) A study published today in JAMA Network Open concludes that 86 percent of diet trials amended their desired study outcomes along the way. That raises the possibility of bias, say researchers David Ludwig, MD, PhD and Cara Ebbeling, PhD, of Boston Children's Hospital, and Steven Heymsfield, MD, of the Pennington Biomedical Research Center (Baton Rouge, Louisiana).