Different mutations in a single gene can wreak many types of havoc in brain cells

(The Mount Sinai Hospital / Mount Sinai School of Medicine) Mount Sinai researchers have found that different mutations in a single gene can have myriad effects on a person's health, suggesting that gene therapies may need to do more than just replenish the missing or dysfunctional protein the gene is supposed to encode, according to a study published in Nature Genetics in November 2019.