CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

(Wellcome Trust Sanger Institute) A comprehensive map of genes necessary for cancer survival is one step closer, following validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types. Scientists at the Wellcome Sanger Institute and the Broad Institute of MIT and Harvard compared the consistency of the two datasets, independently verifying the methodology and findings. Published in Nature Communications, the study will help speed the discovery ...