Alzheimer 'tau' protein far surpasses amyloid in predicting toll on brain tissue

(University of California - San Francisco) The results, published Jan. 1, 2020 in Science Translational Medicine, support researchers' growing recognition that tau drives brain degeneration in Alzheimer's disease more directly than amyloid protein, and at the same time demonstrates the potential of recently developed tau-based PET (positron emission tomography) brain imaging technology to accelerate Alzheimer's clinical trials and improve individualized patient care.