Brazilian scientists unveil chemotherapy resistance mechanism related to p53 mutation

(Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem (INBEB)) Brazilian study uncovered an anticancer chemotherapy resistance mechanism related to amyloid aggregation of mutant p53. The research was conducted in cells derived from glioblastoma, a super aggressive brain tumor, and in living cells. The results open up new opportunities for the development of more effective therapies against cancer.