Bad to the bone: Specific gut bacterium impairs normal skeletal growth and maturation

(Medical University of South Carolina) Bone mass accrual is regulated by the gut microbiome as well as by diet and exercise. In a new report, researchers at the Medical University of South Carolina showed that a specific gut bacterium, segmented filamentous bacteria, influences particular immune responses in the gut and liver. These immune response changes lead to increased bone resorbing osteoclast and suppressed bone forming osteoblast activity, which impaired bone mass accrual during post-pub...