Moffitt researchers identify molecular pathway that controls immunosuppression in tumors

(H. Lee Moffitt Cancer Center & Research Institute) In a new article published in the journal Immunity, Moffitt Cancer Center researchers reveas how protein-signaling pathways associated with cellular stress processes turn myeloid cells into tumor-promoting players. They also suggest that targeting the PERK protein may be an effective therapeutic approach to reactivate the immune system and boost the effectiveness of immunotherapy.