Preventing pancreatic cancer metastasis by keeping cells 'sheltered in place'

(Sanford Burnham Prebys Medical Discovery Institute) Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that pancreatic cancer metastasis--when tumor cells gain the deadly ability to migrate to new parts of the body--can be suppressed by inhibiting a protein called Slug that regulates cell movement. The study, published in the Journal of Experimental Medicine, also revealed two druggable targets that interact with Slug and hold promise as treatments that may stop the spr...