Functional in silico dissection of the brain during the natural wake-sleep cycle

(Universitat Pompeu Fabra - Barcelona) The human brain is a complex system comprising 1010 non-linear units (neurons) that interact in 1015 sites (synapses). Considering such an astonishing level of complexity and heterogeneity, it is surprising that the global dynamics of the brain self-organize into a discrete set of well-defined states.