MHC class II transactivator CIITA induces cell resistance to Ebola Virus and SARS-like coronaviruses

(Benaroya Research Institute at Virginia Mason) Discoveries from the Benaroya Research Institute at Virginia Mason (BRI) have identified a new cellular protection pathway that targets a common vulnerability in several different pandemic viruses, and collaborators at Case Western Reserve University, Boston University School of Medicine and MRIGlobal have shown that this pathway can protect cells from infection by Ebola virus and coronaviruses, like SARS-CoV-2. Published today in Science, these ne...