High-dose equal to standard flu vaccine for risk of death or heart, lung hospitalization

(American Heart Association) A high-dose, trivalent influenza vaccine was no more effective than the standard-dose quadrivalent vaccine at reducing the risk of death or hospitalization for heart or lung-related causes among patients with heart disease.While overall there were few serious side effects in both vaccine groups, those who received the high-dose vaccine had more injection-related side effects such as pain, swelling and muscle aches.