New insight into protein structures that could treat Huntington's disease

(University of Groningen) In Huntington's disease, a faulty protein aggregates in brain cells and eventually kills them. Such protein aggregates could, in principle, be prevented with a heat shock protein. However, it is not well known how these proteins interact with the Huntington's disease protein. New research by Patrick van der Wel (University of Groningen) and colleagues at the University of Texas has partially resolved the structure of heat shock proteins that bind to such aggregating pro...