Amyloid plaque mutation map opens new avenues for early detection of Alzheimer's disease

(Center for Genomic Regulation) Researchers have mapped all possible mutations in the amyloid beta peptide and tested how this influences its aggregation into plaques, a pathological hallmark of Alzheimer's disease. The comprehensive mutation map, which is the first of its kind, can help predict whether a mutation can make an individual more prone to developing Alzheimer's disease later in life. It will also help researchers better understand the biological mechanisms that control the onset of t...