Investigational gene regulation therapy could protect against Alzheimer's

(DZNE - German Center for Neurodegenerative Diseases) Researchers at the DZNE, Massachusetts General Hospital and Sangamo Therapeutics, Inc. tested a novel gene regulation approach to treat brain diseases such as Alzheimer's in laboratory studies. It leverages zinc finger proteins, which specifically bind to the DNA that codes for the protein Tau without altering it, thereby reducing Tau production in the brain and preventing nerve damage. The preclinical results, published in Science Advances, ...