Novel pharmacological strategies to treat alcoholism. Focus on epigenetics

(Bentham Science Publishers) This study explores the impact of alcohol on epigenetics, a term that defines chemical modifications of DNA (without changing its nucleotide sequence), proteins and mRNA (messenger RNA), and the action of regulatory non-coding RNAs. Epigenetic changes affect the adequate functioning of cellular events such as protein synthesis, protein trafficking, metabolic control, or energy production. Besides, the study examines new chemical agents that may interfere with ethanol...