Scientists reveal elusive inner workings of antioxidant enzyme with therapeutic potential

The enzyme manganese superoxide dismutase (MnSOD) plays a critical role in maintaining human health by keeping the amount of harmful reactive oxygen molecules in cells under control. By using neutron scattering, researchers have now obtained a complete atomic portrait of the enzyme, revealing key information about its catalytic mechanism. The work could help experts develop MnSOD-based treatments and design therapeutics that mimic its antioxidant behavior.