Metabolite fumarate can reveal cell damage: New method to generate fumarate for MRI

(Johannes Gutenberg Universitaet Mainz) A promising new concept presented by an interdisciplinary research team paves the way for major advances in the field of magnetic resonance imaging (MRI). Their new technique could significantly simplify hyperpolarized MRI. The proposal involves the hyperpolarization of the metabolic product fumarate using parahydrogen and the subsequent purification of the metabolite.