Ludwig Cancer Research study shows pancreatic cancer cells reverse to advance malignancy

(Ludwig Institute for Cancer Research) A Ludwig Cancer Research study has identified a previously unrecognized mechanism by which cancer cells of a relatively benign subtype of pancreatic tumors methodically revert--or "de-differentiate"--to a progenitor, or immature, state of cellular development to spawn highly aggressive tumors that are capable of metastasis to the liver and lymph nodes.