Identifying how chemotherapy drug works could deliver personalized cancer treatment

(The Korea Advanced Institute of Science and Technology (KAIST)) Researchers have identified the genetic and molecular mechanisms within cells that make the chemotherapy drug decitabine--used to treat patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) --work for some patients but not others. The findings should assist clinicians in developing more patient-specific treatment strategies.