Lactate reveals all about its antidepressant prowess

(National Center of Competence in Research Synapsy) Neuroscientists from Synapsy have demonstrated that lactate, a molecule produced during exercise, has an antidepressant effect in mice. Yet it can also counter the inhibition of the survival and proliferation of new neurons, a loss seen in patients suffering from depression. Furthermore, they pinpointed NADH derived from the metabolism of lactate, as a vital mechanistic component. These findings should lead to an improvement in the way depressi...