'Suffocating' cancer: A new headway in melanoma immunotherapy

(Luxembourg Institute of Health) Led by Dr. Bassam Janji, from the Luxembourg Institute of Health, the team used gene editing technologies to show how targeting HIF-1α could not only inhibit tumor growth, but also drive cytotoxic immune cells to the cancer tissue. This discovery provided a valuable new target to make resistant melanomas more vulnerable to available anti-cancer treatments. Their findings were recently published in the reputable Oncogene journal.